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VOL. 8, ISSUE 1 (2026)
Chemical composition of paracetamol determined by IR spectroscopy
Authors
Ioana Stanciu
Abstract
In this article we determined the chemical
composition of paracetamol using the ShemadzuIRPrestige-21 spectrophotometer.
The IR spectrum of paracetamol contains the following bands of groups O-H, CH3,
C=O, C=C, N-H, C-H, C-C, C-N (aryl) and C-N (amide). Paracetamol
(acetaminophen) is a widely used analgesic and antipyretic, structurally
characterized by a para-aminophenol nucleus, which gives it a specific
pharmacological profile. The active substance, N-acetyl-p-aminophenol, is
formulated in various pharmaceutical presentations, from tablets and capsules
to oral solutions or suppositories. In these forms, paracetamol is accompanied
by excipients such as fillers, disintegrants, sweeteners, stabilizers or flavor
correctors, which ensure stability, solubility and optimal bioavailability. Its
relatively simple chemical composition, combined with a favorable tolerability
profile, explains the use of paracetamol as a first-line drug in the management
of pain and fever.
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Pages:29-31
How to cite this article:
Ioana Stanciu "Chemical composition of paracetamol determined by IR spectroscopy". International Journal of Educational Research and Development, Vol 8, Issue 1, 2026, Pages 29-31
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