ARCHIVES
VOL. 6, ISSUE 1 (2024)
Exploration of the healing effect of red betel leaf essential oil ointment on incision wounds in wistar rats (Rattus Norvegicus)
Authors
Deng Dongwen, Fioni
Abstract
The red betel plant (Piper crocatum) is abundant in medicinal
compounds, primarily found in its leaves, including essential oils, alkaloids,
saponins, tannins, and flavonoids. Chromatogram results confirm the presence of
these compounds, providing a robust scientific basis for using red betel in
traditional medicine. Renowned for its antiseptic and antibacterial properties,
red betel’s chemical elements contribute to its treatment efficacy. This study,
conducted in January 2024, aimed to assess the effectiveness of ointment
derived from the essential oil of red betel leaves (Piper crocatum Linn.) in
healing wounds in Wistar rats (Rattus norvegicus). Using an experimental
approach with a Pre-test and Post-test group-only control design, the study
involved 25 randomly selected white male rats divided into five groups (four
treatment groups and one control group), each consisting of five rats. The
essential oil Saleb of red betel leaf extract (Piper crocatum Linn.) contains
bioactive compounds like alkaloids, flavonoids, saponins, and tannins,
contributing to its role in wound healing. The optimal concentration for recovery
of cut wounds in white rats is 9% v/v. The highest healing percentage on day 14
was observed in the positive control (Bioplacenton®) at 95%, followed by the 9%
v/v extract with a 90% healing rate. The essential oil Saleb preparation of red
betel leaf extract (Piper crocatum Linn.) demonstrates efficacy comparable to
Bioplacenton® in recovering cut wounds in rats.
Download
Pages:52-55
How to cite this article:
Deng Dongwen, Fioni "Exploration of the healing effect of red betel leaf essential oil ointment on incision wounds in wistar rats (Rattus Norvegicus)". International Journal of Educational Research and Development, Vol 6, Issue 1, 2024, Pages 52-55
Download Author Certificate
Please enter the email address corresponding to this article submission to download your certificate.